Since sucralose is a non-nutritive substitute for sugar, it has no actual and direct health benefits, but has many indirect benefits. It is well known that sugar intake is strongly associated with dental caries (tooth decay) and periodontal (gum) disease. The use of sucralose can reduce sugar intake, which is good for dental health, so it will not cause caries.
Sucralose is used as a nonnutritive sweetener in many low-calorie products. It is also beneficial for weight loss and obesity-related diseases, including cardiovascular disease (CVD), type 2 diabetes, polycystic ovary syndrome, and some cancers. Sucralose does not affect hunger, nor does it trigger an insulin response.
In addition to causing obesity, sugar is also a risk factor for cardiovascular disease due to its potential to increase serum triglycerides. So, by replacing sugar with sucralose, you can reduce your risk of heart disease, stroke, and prevent high insulin levels.
Because sucralose does not affect blood sugar or serum insulin levels, it is also suitable for people with type 1 and type 2 diabetes.